Structural analysis of recombinant human ubiquitin-conjugating enzyme UbcH5c

UbcH5c belongs to the ubiquitin-conjugating enzyme family and plays an important role in catalyzing ubiquitination during TNF-α--triggered NF-κB activation. Therefore, UbcH5c is a potent therapeutic target for the treatment of inflammatory and autoimmune diseases induced by aberrant activation of NF...

Täydet tiedot

Bibliografiset tiedot

Päätekijät:	Fangshu Wu, Junsheng Zhu, Honglin Li, Lili Zhu
Aineistotyyppi:	Artigo
Kieli:	Inglês
Julkaistu:	Elsevier 2017-05-01
Sarja:	Acta Pharmaceutica Sinica B
Aiheet:	UbcH5c NF-κB Ubiquitination Ubiquitin-conjugating enzyme Crystal structure Inflammatory target
Linkit:	http://www.sciencedirect.com/science/article/pii/S2211383516303677
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