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NEDD4 regulates ubiquitination and stability of the cell adhesion molecule IGPR-1 via lysosomal pathway

Abstract Background The cell adhesion molecule IGPR-1 regulates various critical cellular processes including, cell–cell adhesion, mechanosensing and autophagy and plays important roles in angiogenesis and tumor growth; however, the molecular mechanism governing the cell surface levels of IGPR-1 rem...

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Principais autores: Linzi Sun, Razie Amraei, Nader Rahimi
Format: Artigo
Sprog:Inglês
Udgivet: BMC 2021-05-01
Serier:Journal of Biomedical Science
Fag:
NEDD4
IGPR-1
TMIGD2
CD28H
UbcH6
Ubiquitination
Online adgang:https://doi.org/10.1186/s12929-021-00731-9
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