Comparison of substrate specificity of the ubiquitin ligases Nedd4 and Nedd4‐2 using proteome arrays

Abstract Target recognition by the ubiquitin system is mediated by E3 ubiquitin ligases. Nedd4 family members are E3 ligases comprised of a C2 domain, 2–4 WW domains that bind PY motifs (L/PPxY) and a ubiquitin ligase HECT domain. The nine Nedd4 family proteins in mammals include two close relatives...

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主要な著者:	Avinash Persaud, Philipp Alberts, Eva M Amsen, Xuejian Xiong, James Wasmuth, Zachary Saadon, Chris Fladd, John Parkinson, Daniela Rotin
フォーマット:	Artigo
言語:	Inglês
出版事項:	Springer Nature 2009-12-01
シリーズ:	Molecular Systems Biology
主題:	E3 ubiquitin ligase HECT domain Nedd4 proteome array ubiquitin
オンライン･アクセス:	https://doi.org/10.1038/msb.2009.85
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