Protein motions during catalysis by dihydrofolate reductases

Dihydrofolate reductase (DHFR) maintains the intracellular pool of tetrahydrofolate through catalysis of hydrogen transfer from reduced nicotinamide adenine dinucleotide to 7,8-dihydrofolate. We report results for pre-steady-state kinetic studies of the temperature dependence of the rates and the hy...

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Bibliografiske detaljer
Main Authors: Allemann, Rudolf K, Evans, Rhiannon M, Tey, Lai-hock, Maglia, Giovanni, Pang, Jiayun, Rodriguez, Robert, Shrimpton, Paul J, Swanwick, Richard S
Format: Artigo
Sprog:Inglês
Udgivet: The Royal Society 2006
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1647303/
https://ncbi.nlm.nih.gov/pubmed/16873119
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rstb.2006.1865
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