Regression of established tumors and metastases by potent vascular endothelial growth factor blockade

Vascular endothelial growth factor (VEGF) is a critical promoter of blood vessel growth during embryonic development and tumorigenesis. To date, studies of VEGF antagonists have primarily focused on halting progression in models of minimal residual cancer. Consistent with this focus, recent clinical...

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Autori principali: Huang, Jianzhong, Frischer, Jason S., Serur, Anna, Kadenhe, Angela, Yokoi, Akiko, McCrudden, Kimberly W., New, Tamara, O'Toole, Kathleen, Zabski, Stephanie, Rudge, John S., Holash, Jocelyn, Yancopoulos, George D., Yamashiro, Darrell J., Kandel, Jessica J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2003
Soggetti:
Biological Sciences
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC164665/
https://ncbi.nlm.nih.gov/pubmed/12805568
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1432908100
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