Inhibition of cyclo-oxygenase 2 reduces tumor metastasis and inflammatory signaling during blockade of vascular endothelial growth factor

Vascular endothelial growth factor (VEGF) blockade is an effective therapy for human cancer, yet virtually all neoplasms resume primary tumor growth or metastasize during therapy. Mechanisms of progression have been proposed to include genes that control vascular remodeling and are elicited by hypop...

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Main Authors: Fisher, Jason C, Gander, Jeffrey W, Haley, Mary Jo, Hernandez, Sonia L, Huang, Jianzhong, Chang, Yan-Jung, Johung, Tessa B, Guarnieri, Paolo, O'Toole, Kathleen, Yamashiro, Darrell J, Kandel, Jessica J
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2011
Teme:
Research
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3198683/
https://ncbi.nlm.nih.gov/pubmed/21978392
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2045-824X-3-22
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