Inhibition of cyclo-oxygenase 2 reduces tumor metastasis and inflammatory signaling during blockade of vascular endothelial growth factor

Vascular endothelial growth factor (VEGF) blockade is an effective therapy for human cancer, yet virtually all neoplasms resume primary tumor growth or metastasize during therapy. Mechanisms of progression have been proposed to include genes that control vascular remodeling and are elicited by hypop...

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Bibliografiske detaljer
Main Authors: Fisher, Jason C, Gander, Jeffrey W, Haley, Mary Jo, Hernandez, Sonia L, Huang, Jianzhong, Chang, Yan-Jung, Johung, Tessa B, Guarnieri, Paolo, O'Toole, Kathleen, Yamashiro, Darrell J, Kandel, Jessica J
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2011
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3198683/
https://ncbi.nlm.nih.gov/pubmed/21978392
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2045-824X-3-22
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