Potent VEGF blockade causes regression of coopted vessels in a model of neuroblastoma

Vascular endothelial growth factor (VEGF) plays a key role in human tumor angiogenesis. We compared the effects of inhibitors of VEGF with different specificities in a xenograft model of neuroblastoma. Cultured human neuroblastoma NGP-GFP cells were implanted intrarenally in nude mice. Three anti-VE...

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Detalhes bibliográficos
Main Authors: Kim, Eugene S., Serur, Anna, Huang, Jianzhong, Manley, Christina A., McCrudden, Kimberly W., Frischer, Jason S., Soffer, Samuel Z., Ring, Laurence, New, Tamara, Zabski, Stephanie, Rudge, John S., Holash, Jocelyn, Yancopoulos, George D., Kandel, Jessica J., Yamashiro, Darrell J.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2002
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC123268/
https://ncbi.nlm.nih.gov/pubmed/12177446
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.172398399
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