Potent VEGF blockade causes regression of coopted vessels in a model of neuroblastoma

Vascular endothelial growth factor (VEGF) plays a key role in human tumor angiogenesis. We compared the effects of inhibitors of VEGF with different specificities in a xenograft model of neuroblastoma. Cultured human neuroblastoma NGP-GFP cells were implanted intrarenally in nude mice. Three anti-VE...

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Tallennettuna:
Bibliografiset tiedot
Päätekijät: Kim, Eugene S., Serur, Anna, Huang, Jianzhong, Manley, Christina A., McCrudden, Kimberly W., Frischer, Jason S., Soffer, Samuel Z., Ring, Laurence, New, Tamara, Zabski, Stephanie, Rudge, John S., Holash, Jocelyn, Yancopoulos, George D., Kandel, Jessica J., Yamashiro, Darrell J.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: National Academy of Sciences 2002
Aiheet:
Biological Sciences
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC123268/
https://ncbi.nlm.nih.gov/pubmed/12177446
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.172398399
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