Notch suppresses angiogenesis and progression of hepatic metastases

The Notch pathway plays multiple key roles in tumorigenesis, and its signaling components have therefore aroused great interest as targets for emerging therapies. Here we show that inhibition of Notch, using a soluble receptor Notch1 decoy, unexpectedly caused a remarkable increase in liver metastas...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Cancer Res
Main Authors: Banerjee, Debarshi, Hernandez, Sonia L., Garcia, Alejandro, Kangsamaksin, Thaned, Sbiroli, Emily, Andrews, John, Forrester, Lynn Ann, Wei, Na, Kadenhe-Chiweshe, Angela, Shawber, Carrie J., Kitajewski, Jan K., Kandel, Jessica J., Yamashiro, Darrell J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4401639/
https://ncbi.nlm.nih.gov/pubmed/25744722
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-14-1493
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados