Adoptive transfer of apoptotic splenocytes worsens survival, whereas adoptive transfer of necrotic splenocytes improves survival in sepsis

In sepsis, both necrotic and apoptotic cell death can occur. Apoptotic cells induce anergy that could impair the host response, whereas necrotic cells cause immune activation that might result in enhanced antimicrobial defenses. We determined whether adoptive transfer of apoptotic or necrotic cells...

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Hauptverfasser: Hotchkiss, Richard S., Chang, Katherine C., Grayson, Mitchell H., Tinsley, Kevin W., Dunne, Benjamin S., Davis, Christopher G., Osborne, Dale F., Karl, Irene E.
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2003
Schlagworte:
Biological Sciences
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC164514/
https://ncbi.nlm.nih.gov/pubmed/12736377
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1031788100
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