Adoptive Transfer of Ceramide Synthase 6 Deficient Splenocytes Reduces the Development of Colitis

Sphingolipids regulate critical cellular processes including inflammation. Ceramide, which serves a central role in sphingolipid metabolism, is generated by six ceramide synthases (CerS) that differ in substrate specificity. CerS6 preferentially generates C(16)-ceramide and its mRNA is highly expres...

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Опубликовано в: :Sci Rep
Главные авторы: Scheffel, Matthew J., Helke, Kristi, Lu, Ping, Bowers, Jacob S., Ogretmen, Besim, Garrett-Mayer, Elizabeth, Paulos, Chrystal M., Voelkel-Johnson, Christina
Формат: Artigo
Язык:Inglês
Опубликовано: Nature Publishing Group UK 2017
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5686186/
https://ncbi.nlm.nih.gov/pubmed/29138469
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-15791-x
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