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Ceramide Synthase 6 Maximizes p53 Function to Prevent Progeny Formation from Polyploid Giant Cancer Cells

SIMPLE SUMMARY: One mechanism that contributes to cancer recurrence is the ability of some malignant cells to temporarily halt cell division and accumulate multiple nuclei that are later released as progeny, which resume cell division. The release of progeny occurs via primitive cleavage and is high...

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Bibliografische gegevens
Gepubliceerd in:Cancers (Basel)
Hoofdauteurs: Lu, Ping, White-Gilbertson, Shai, Beeson, Gyda, Beeson, Craig, Ogretmen, Besim, Norris, James, Voelkel-Johnson, Christina
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: MDPI 2021
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8125704/
https://ncbi.nlm.nih.gov/pubmed/34062962
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers13092212
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