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Adoptive transfer of apoptotic splenocytes worsens survival, whereas adoptive transfer of necrotic splenocytes improves survival in sepsis

In sepsis, both necrotic and apoptotic cell death can occur. Apoptotic cells induce anergy that could impair the host response, whereas necrotic cells cause immune activation that might result in enhanced antimicrobial defenses. We determined whether adoptive transfer of apoptotic or necrotic cells...

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Autori principali: Hotchkiss, Richard S., Chang, Katherine C., Grayson, Mitchell H., Tinsley, Kevin W., Dunne, Benjamin S., Davis, Christopher G., Osborne, Dale F., Karl, Irene E.
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2003
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC164514/
https://ncbi.nlm.nih.gov/pubmed/12736377
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1031788100
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