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Adoptive transfer of apoptotic splenocytes worsens survival, whereas adoptive transfer of necrotic splenocytes improves survival in sepsis

In sepsis, both necrotic and apoptotic cell death can occur. Apoptotic cells induce anergy that could impair the host response, whereas necrotic cells cause immune activation that might result in enhanced antimicrobial defenses. We determined whether adoptive transfer of apoptotic or necrotic cells...

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Detalhes bibliográficos
Main Authors: Hotchkiss, Richard S., Chang, Katherine C., Grayson, Mitchell H., Tinsley, Kevin W., Dunne, Benjamin S., Davis, Christopher G., Osborne, Dale F., Karl, Irene E.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2003
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC164514/
https://ncbi.nlm.nih.gov/pubmed/12736377
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1031788100
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