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Cytokines and BCR-ABL mediate suppression of TRAIL-induced apoptosis through inhibition of forkhead FOXO3a transcription factor

Cytokine-provided survival signals are known to suppress apoptosis through inhibition of mitochondrial pathways that involve Bcl-2 family members. Here we show that in hematopoietic cells, cytokines also regulate death receptor-mediated pathways. We demonstrate that hematopoietic cytokines such as I...

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Hlavní autoři: Ghaffari, Saghi, Jagani, Zainab, Kitidis, Claire, Lodish, Harvey F., Khosravi-Far, Roya
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2003
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC164479/
https://ncbi.nlm.nih.gov/pubmed/12750477
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0731871100
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