Epidermal growth factor receptor signaling intensity determines intracellular protein interactions, ubiquitination, and internalization

Ligand activation of the epidermal growth factor receptor (EGFR) causes the binding of Cbls, which leads to EGFR polyubiquitination and internalization through endophilin complexes that contain the adaptor protein SH3-domain encoding, expressed in tumorigenic astrocytes/Cbl-interacting protein of 85...

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Pubblicato in:	Proc Natl Acad Sci U S A
Autori principali:	Schmidt, Mirko H. H., Furnari, Frank B., Cavenee, Webster K., Bögler, Oliver
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	National Academy of Sciences 2003
Soggetti:	Biological Sciences
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC164476/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12734385/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.1031790100
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