Epidermal growth factor receptor signaling intensity determines intracellular protein interactions, ubiquitination, and internalization

Ligand activation of the epidermal growth factor receptor (EGFR) causes the binding of Cbls, which leads to EGFR polyubiquitination and internalization through endophilin complexes that contain the adaptor protein SH3-domain encoding, expressed in tumorigenic astrocytes/Cbl-interacting protein of 85...

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Detaylı Bibliyografya
Asıl Yazarlar: Schmidt, Mirko H. H., Furnari, Frank B., Cavenee, Webster K., Bögler, Oliver
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: National Academy of Sciences 2003
Konular:
Biological Sciences
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC164476/
https://ncbi.nlm.nih.gov/pubmed/12734385
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1031790100
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