Epidermal growth factor receptor signaling intensity determines intracellular protein interactions, ubiquitination, and internalization
Ligand activation of the epidermal growth factor receptor (EGFR) causes the binding of Cbls, which leads to EGFR polyubiquitination and internalization through endophilin complexes that contain the adaptor protein SH3-domain encoding, expressed in tumorigenic astrocytes/Cbl-interacting protein of 85...
Saved in:
| Published in: | Proc Natl Acad Sci U S A |
|---|---|
| Main Authors: | , , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
National Academy of Sciences
2003
|
| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC164476/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12734385/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.1031790100 |
| Tags: |
No Tags, Be the first to tag this record!
|