Live Attenuated Influenza Virus Expressing Human Interleukin-2 Reveals Increased Immunogenic Potential in Young and Aged Hosts

Despite the reported efficacy of commercially available influenza virus vaccines, a considerable proportion of the human population does not respond well to vaccination. In an attempt to improve the immunogenicity of live influenza vaccines, an attenuated, cold-adapted (ca) influenza A virus express...

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Bibliographic Details
Main Authors: Ferko, Boris, Kittel, Christian, Romanova, Julia, Sereinig, Sabine, Katinger, Hermann, Egorov, Andrej
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2006
Subjects:
Vaccines and Antiviral Agents
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1642586/
https://ncbi.nlm.nih.gov/pubmed/16971432
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01645-06
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