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Influenza Virus NS Vectors Expressing the Mycobacterium tuberculosis ESAT-6 Protein Induce CD4(+) Th1 Immune Response and Protect Animals against Tuberculosis Challenge

Infection with Mycobacterium tuberculosis remains a major cause of morbidity and mortality all over the world. Since the effectiveness of the only available tuberculosis vaccine, Mycobacterium bovis bacillus Calmette-Guérin (BCG), is suboptimal, there is a strong demand to develop new tuberculosis v...

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Main Authors: Sereinig, Sabine, Stukova, Marina, Zabolotnyh, Natalia, Ferko, Boris, Kittel, Christian, Romanova, Julia, Vinogradova, Tatiana, Katinger, Hermann, Kiselev, Oleg, Egorov, Andrej
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2006
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1539114/
https://ncbi.nlm.nih.gov/pubmed/16893990
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/CVI.00056-06
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