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Generation of an Influenza A Virus Vector Expressing Biologically Active Human Interleukin-2 from the NS Gene Segment

Engineering of the influenza A virus NS1 protein became an attractive approach to the development of influenza vaccine vectors since it can tolerate large inserts of foreign proteins. However, influenza virus vectors expressing long foreign sequences from the NS1 open reading frame (ORF) are usually...

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Detalhes bibliográficos
Main Authors: Kittel, Christian, Ferko, Boris, Kurz, Martina, Voglauer, Regina, Sereinig, Sabine, Romanova, Julia, Stiegler, Gabriela, Katinger, Hermann, Egorov, Andrej
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1182655/
https://ncbi.nlm.nih.gov/pubmed/16051859
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.79.16.10672-10677.2005
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