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Differential selection of multidrug efflux systems by quinolones in Pseudomonas aeruginosa.

Resistance mechanisms selected after in vitro exposure to 12 quinolones were analyzed for Pseudomonas aeruginosa. Efflux-type mutants were predominant. Quinolones differed in their ability to select a particular efflux system. While the newer fluoroquinolones favored the MexCD-OprJ system, the older...

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Bibliografiske detaljer
Udgivet i:Antimicrob Agents Chemother
Principais autores: Köhler, T, Michea-Hamzehpour, M, Plesiat, P, Kahr, A L, Pechere, J C
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 1997
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC164158/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9371363/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.41.11.2540
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