Differential selection of multidrug efflux systems by quinolones in Pseudomonas aeruginosa.

Resistance mechanisms selected after in vitro exposure to 12 quinolones were analyzed for Pseudomonas aeruginosa. Efflux-type mutants were predominant. Quinolones differed in their ability to select a particular efflux system. While the newer fluoroquinolones favored the MexCD-OprJ system, the older...

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Main Authors: Köhler, T, Michea-Hamzehpour, M, Plesiat, P, Kahr, A L, Pechere, J C
Format: Artigo
Jezik:Inglês
Izdano: 1997
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC164158/
https://ncbi.nlm.nih.gov/pubmed/9371363
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