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Overexpression of the MexEF-OprN Multidrug Efflux System Affects Cell-to-Cell Signaling in Pseudomonas aeruginosa

Intrinsic and acquired antibiotic resistance of the nosocomial pathogen Pseudomonas aeruginosa is mediated mainly by the expression of several efflux pumps of broad substrate specificity. Here we report that nfxC type mutants, overexpressing the MexEF-OprN efflux system, produce lower levels of extr...

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Detalhes bibliográficos
Main Authors: Köhler, Thilo, van Delden, Christian, Curty, Lasta Kocjancic, Hamzehpour, Mehri Michea, Pechere, Jean-Claude
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2001
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC95401/
https://ncbi.nlm.nih.gov/pubmed/11514502
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.183.18.5213-5222.2001
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