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Overexpression of the MexEF-OprN Multidrug Efflux System Affects Cell-to-Cell Signaling in Pseudomonas aeruginosa

Intrinsic and acquired antibiotic resistance of the nosocomial pathogen Pseudomonas aeruginosa is mediated mainly by the expression of several efflux pumps of broad substrate specificity. Here we report that nfxC type mutants, overexpressing the MexEF-OprN efflux system, produce lower levels of extr...

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Autori principali: Köhler, Thilo, van Delden, Christian, Curty, Lasta Kocjancic, Hamzehpour, Mehri Michea, Pechere, Jean-Claude
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2001
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC95401/
https://ncbi.nlm.nih.gov/pubmed/11514502
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.183.18.5213-5222.2001
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