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Overexpression of the MexEF-OprN Multidrug Efflux System Affects Cell-to-Cell Signaling in Pseudomonas aeruginosa

Intrinsic and acquired antibiotic resistance of the nosocomial pathogen Pseudomonas aeruginosa is mediated mainly by the expression of several efflux pumps of broad substrate specificity. Here we report that nfxC type mutants, overexpressing the MexEF-OprN efflux system, produce lower levels of extr...

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Publicado en:J Bacteriol
Autores principales: Köhler, Thilo, van Delden, Christian, Curty, Lasta Kocjancic, Hamzehpour, Mehri Michea, Pechere, Jean-Claude
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology (ASM) 2001
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Acceso en línea:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC95401/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11514502/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JB.183.18.5213-5222.2001
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