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Carbapenem Activities against Pseudomonas aeruginosa: Respective Contributions of OprD and Efflux Systems

While meropenem MICs were strongly influenced by the presence or absence of the MexAB-OprM efflux pump in both OprD-proficient and -deficient strain backgrounds, MICs of imipenem and of ER-35786 remained unchanged, demonstrating that meropenem is a substrate of MexAB-OprM but not imipenem and ER-357...

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Detalhes bibliográficos
Main Authors: Köhler, Thilo, Michea-Hamzehpour, Mehri, Epp, Simone F., Pechere, Jean-Claude
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 1999
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC89097/
https://ncbi.nlm.nih.gov/pubmed/9925552
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