Characterization of a new TEM-derived beta-lactamase produced in a Serratia marcescens strain.

A natural TEM variant beta-lactamase was isolated from an epidemic strain of Serratia marcescens. Nucleotide gene sequencing revealed multiple point mutations located in the 42-to-44 tripeptide and positions 145 to 146, 178, and 238. In addition, a glutamic acid 212 deletion was also found. The puri...

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Pubblicato in:	Antimicrob Agents Chemother
Autori principali:	Perilli, M, Felici, A, Franceschini, N, De Santis, A, Pagani, L, Luzzaro, F, Oratore, A, Rossolini, G M, Knox, J R, Amicosante, G
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 1997
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC164131/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9371336/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.41.11.2374
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