Characterization of a new TEM-derived beta-lactamase produced in a Serratia marcescens strain.

A natural TEM variant beta-lactamase was isolated from an epidemic strain of Serratia marcescens. Nucleotide gene sequencing revealed multiple point mutations located in the 42-to-44 tripeptide and positions 145 to 146, 178, and 238. In addition, a glutamic acid 212 deletion was also found. The puri...

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Autori principali: Perilli, M, Felici, A, Franceschini, N, De Santis, A, Pagani, L, Luzzaro, F, Oratore, A, Rossolini, G M, Knox, J R, Amicosante, G
Natura: Artigo
Lingua:Inglês
Pubblicazione: 1997
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC164131/
https://ncbi.nlm.nih.gov/pubmed/9371336
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