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In vitro activities of the biguanide PS-15 and its metabolite, WR99210, against cycloguanil-resistant Plasmodium falciparum isolates from Thailand.

The in vitro activities of the new biguanide PS-15 and its putative active metabolite, WR99210, were determined against seven different isolates or clones of Plasmodium falciparum. The mean 50% inhibitory concentrations of PS-15 and WR99210 were 1,015 and 0.06 ng/ml, respectively. WR99210 was up to...

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Bibliografiska uppgifter
Huvudupphovsmän: Edstein, M D, Bahr, S, Kotecka, B, Shanks, G D, Rieckmann, K H
Materialtyp: Artigo
Språk:Inglês
Publicerad: 1997
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC164114/
https://ncbi.nlm.nih.gov/pubmed/9333069
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