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Role of embB in natural and acquired resistance to ethambutol in mycobacteria.

The mycobacterial embCAB operon encodes arabinosyl transferases, putative targets of the antimycobacterial agent ethambutol (EMB). Mutations in embB lead to resistance to EMB in Mycobacterium tuberculosis. The basis for natural, intrinsic resistance to EMB in nontuberculous mycobacteria (NTM) is not...

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書誌詳細
出版年:Antimicrob Agents Chemother
主要な著者: Alcaide, F, Pfyffer, G E, Telenti, A
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Microbiology (ASM) 1997
主題:
オンライン・アクセス:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC164105/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9333060/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.41.10.2270
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