Role of embB in natural and acquired resistance to ethambutol in mycobacteria.

The mycobacterial embCAB operon encodes arabinosyl transferases, putative targets of the antimycobacterial agent ethambutol (EMB). Mutations in embB lead to resistance to EMB in Mycobacterium tuberculosis. The basis for natural, intrinsic resistance to EMB in nontuberculous mycobacteria (NTM) is not...

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Veröffentlicht in:	Antimicrob Agents Chemother
Hauptverfasser:	Alcaide, F, Pfyffer, G E, Telenti, A
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Microbiology (ASM) 1997
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC164105/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9333060/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.41.10.2270
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