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Role of embB in natural and acquired resistance to ethambutol in mycobacteria.

The mycobacterial embCAB operon encodes arabinosyl transferases, putative targets of the antimycobacterial agent ethambutol (EMB). Mutations in embB lead to resistance to EMB in Mycobacterium tuberculosis. The basis for natural, intrinsic resistance to EMB in nontuberculous mycobacteria (NTM) is not...

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Detalles Bibliográficos
Publicado en:Antimicrob Agents Chemother
Principais autores: Alcaide, F, Pfyffer, G E, Telenti, A
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology (ASM) 1997
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Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC164105/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9333060/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.41.10.2270
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