Role of embB in natural and acquired resistance to ethambutol in mycobacteria.

The mycobacterial embCAB operon encodes arabinosyl transferases, putative targets of the antimycobacterial agent ethambutol (EMB). Mutations in embB lead to resistance to EMB in Mycobacterium tuberculosis. The basis for natural, intrinsic resistance to EMB in nontuberculous mycobacteria (NTM) is not...

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Detalhes bibliográficos

Publicado no:	Antimicrob Agents Chemother
Principais autores:	Alcaide, F, Pfyffer, G E, Telenti, A
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1997
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC164105/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9333060/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.41.10.2270
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