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SCH 48973: a potent, broad-spectrum, antienterovirus compound.

SCH 48973 is a novel molecule with potent, selective, antienterovirus activity. In assays of the cytopathic effect against five picornaviruses, SCH 48973 had antiviral activity (50% inhibitory concentrations [IC50s]) of 0.02 to 0.11 microg/ml, with no detectable cytotoxicity at 50 microg/ml. SCH 489...

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Publicado no:Antimicrob Agents Chemother
Principais autores: Buontempo, P J, Cox, S, Wright-Minogue, J, DeMartino, J L, Skelton, A M, Ferrari, E, Albin, R, Rozhon, E J, Girijavallabhan, V, Modlin, J F, O'Connell, J F
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1997
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC163890/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9174174/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.41.6.1220
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