SCH 48973: a potent, broad-spectrum, antienterovirus compound.

SCH 48973 is a novel molecule with potent, selective, antienterovirus activity. In assays of the cytopathic effect against five picornaviruses, SCH 48973 had antiviral activity (50% inhibitory concentrations [IC50s]) of 0.02 to 0.11 microg/ml, with no detectable cytotoxicity at 50 microg/ml. SCH 489...

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Main Authors: Buontempo, P J, Cox, S, Wright-Minogue, J, DeMartino, J L, Skelton, A M, Ferrari, E, Albin, R, Rozhon, E J, Girijavallabhan, V, Modlin, J F, O'Connell, J F
Format: Artigo
Sprog:Inglês
Udgivet: 1997
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC163890/
https://ncbi.nlm.nih.gov/pubmed/9174174
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