SCH 48973: a potent, broad-spectrum, antienterovirus compound.

SCH 48973 is a novel molecule with potent, selective, antienterovirus activity. In assays of the cytopathic effect against five picornaviruses, SCH 48973 had antiviral activity (50% inhibitory concentrations [IC50s]) of 0.02 to 0.11 microg/ml, with no detectable cytotoxicity at 50 microg/ml. SCH 489...

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Dades bibliogràfiques

Publicat a:	Antimicrob Agents Chemother
Autors principals:	Buontempo, P J, Cox, S, Wright-Minogue, J, DeMartino, J L, Skelton, A M, Ferrari, E, Albin, R, Rozhon, E J, Girijavallabhan, V, Modlin, J F, O'Connell, J F
Format:	Artigo
Idioma:	Inglês
Publicat:	American Society for Microbiology (ASM) 1997
Matèries:	Research Article
Accés en línia:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC163890/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9174174/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.41.6.1220
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