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Essential role of endogenously synthesized tylosin for induction of ermSF in Streptomyces fradiae.

We compared ermSF induction in wild-type Streptomyces fradiae NRRL B-2702 and that in GS-14, a tylA mutant which cannot synthesize tylosin. Our findings suggest that (i) endogenously synthesized tylosin plays an obligatory role in ermSF induction and (ii) tylosin, or a biosynthetic intermediate beyo...

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Main Authors: Memili, E, Weisblum, B
格式: Artigo
語言:Inglês
出版: 1997
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC163883/
https://ncbi.nlm.nih.gov/pubmed/9145902
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