Essential role of endogenously synthesized tylosin for induction of ermSF in Streptomyces fradiae.

We compared ermSF induction in wild-type Streptomyces fradiae NRRL B-2702 and that in GS-14, a tylA mutant which cannot synthesize tylosin. Our findings suggest that (i) endogenously synthesized tylosin plays an obligatory role in ermSF induction and (ii) tylosin, or a biosynthetic intermediate beyo...

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Vydáno v:	Antimicrob Agents Chemother
Hlavní autoři:	Memili, E, Weisblum, B
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	American Society for Microbiology (ASM) 1997
Témata:	Research Article
On-line přístup:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC163883/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9145902/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.41.5.1203
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