Essential role of endogenously synthesized tylosin for induction of ermSF in Streptomyces fradiae.
We compared ermSF induction in wild-type Streptomyces fradiae NRRL B-2702 and that in GS-14, a tylA mutant which cannot synthesize tylosin. Our findings suggest that (i) endogenously synthesized tylosin plays an obligatory role in ermSF induction and (ii) tylosin, or a biosynthetic intermediate beyo...
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| Pubblicato in: | Antimicrob Agents Chemother |
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| Autori principali: | , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Society for Microbiology (ASM)
1997
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC163883/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9145902/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.41.5.1203 |
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