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Human RNA-specific adenosine deaminase ADAR1 transcripts possess alternative exon 1 structures that initiate from different promoters, one constitutively active and the other interferon inducible

RNA-specific adenosine deaminase (ADAR1) catalyzes the deamination of adenosine to inosine in viral and cellular RNAs. Two size forms of the ADAR1 editing enzyme are known, an IFN-inducible ≈150-kDa protein and a constitutively expressed N-terminally truncated ≈110-kDa protein. We have now identifie...

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Detalhes bibliográficos
Main Authors: George, Cyril X., Samuel, Charles E.
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 1999
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC16382/
https://ncbi.nlm.nih.gov/pubmed/10200312
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