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Protein Kinase PKR and RNA Adenosine Deaminase ADAR1: New Roles for Old Players as Modulators of the Interferon Response

Double-stranded RNA (dsRNA) plays a centrally important role in antiviral innate immunity, both for the production of interferon (IFN) and also in the actions of IFN. Among the IFN inducible gene products are the protein kinase regulated by RNA (PKR) and the adenosine deaminase acting on RNA (ADAR1)...

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Detalhes bibliográficos
Main Authors: Pfaller, Christian K., Li, Zhiqun, George, Cyril X., Samuel, Charles E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3190076/
https://ncbi.nlm.nih.gov/pubmed/21924887
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.coi.2011.08.009
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