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Tipping the Balance: Antagonism of PKR Kinase and ADAR1 Deaminase Functions by Virus Gene Products

The protein kinase regulated by RNA (PKR) and the adenosine deaminase acting on RNA (ADAR1) are interferon-inducible enzymes that play important roles in biologic processes including the antiviral actions of interferons, signal transduction, and apoptosis. PKR catalyzes the RNA-dependent phosphoryla...

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Detalhes bibliográficos
Main Authors: George, Cyril X., Li, Zhiqun, Okonski, Kristina M., Toth, Ann M., Wang, Ying, Samuel, Charles E.
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc. 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2956706/
https://ncbi.nlm.nih.gov/pubmed/19715457
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/jir.2009.0065
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