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STAT2-dependent induction of RNA adenosine deaminase ADAR1 by type I interferon differs between mouse and human cells in the requirement for STAT1

Expression of adenosine deaminase acting on RNA1 (ADAR1) is driven by alternative promoters. Promoter P(A), activated by interferon (IFN), produces transcripts that encode the inducible p150 ADAR1 protein, whereas P(B) specifies the constitutively expressed p110 protein. We show using Stat1(−/−), St...

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Detalhes bibliográficos
Publicado no:Virology
Main Authors: George, Cyril X., Samuel, Charles E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4619148/
https://ncbi.nlm.nih.gov/pubmed/26335850
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2015.08.001
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