Thrombocytopenia and kidney disease in mice with a mutation in the C1galt1 gene

An N-ethyl-N-nitrosourea mutagenesis screen in mice was performed to isolate regulators of circulating platelet number. We report here recessive thrombocytopenia and kidney disease in plt1 mice, which is the result of a severe but partial loss-of-function mutation in the gene encoding glycoprotein-N...

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Bibliografski detalji
Glavni autori: Alexander, Warren S., Viney, Elizabeth M., Zhang, Jian-Guo, Metcalf, Donald, Kauppi, Maria, Hyland, Craig D., Carpinelli, Marina R., Stevenson, William, Croker, Ben A., Hilton, Adrienne A., Ellis, Sarah, Selan, Carly, Nandurkar, Harshal H., Goodnow, Christopher C., Kile, Benjamin T., Nicola, Nicos A., Roberts, Andrew W., Hilton, Douglas J.
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2006
Teme:
Biological Sciences
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1637601/
https://ncbi.nlm.nih.gov/pubmed/17062753
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0607872103
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