Thrombocytopenia and kidney disease in mice with a mutation in the C1galt1 gene

An N-ethyl-N-nitrosourea mutagenesis screen in mice was performed to isolate regulators of circulating platelet number. We report here recessive thrombocytopenia and kidney disease in plt1 mice, which is the result of a severe but partial loss-of-function mutation in the gene encoding glycoprotein-N...

وصف كامل

محفوظ في:
التفاصيل البيبلوغرافية
المؤلفون الرئيسيون: Alexander, Warren S., Viney, Elizabeth M., Zhang, Jian-Guo, Metcalf, Donald, Kauppi, Maria, Hyland, Craig D., Carpinelli, Marina R., Stevenson, William, Croker, Ben A., Hilton, Adrienne A., Ellis, Sarah, Selan, Carly, Nandurkar, Harshal H., Goodnow, Christopher C., Kile, Benjamin T., Nicola, Nicos A., Roberts, Andrew W., Hilton, Douglas J.
التنسيق: Artigo
اللغة:Inglês
منشور في: National Academy of Sciences 2006
الموضوعات:
Biological Sciences
الوصول للمادة أونلاين:https://ncbi.nlm.nih.gov/pmc/articles/PMC1637601/
https://ncbi.nlm.nih.gov/pubmed/17062753
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0607872103
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