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General structural motifs of amyloid protofilaments
Human CA150, a transcriptional activator, binds to and is co-deposited with huntingtin during Huntington's disease. The second WW domain of CA150 is a three-stranded β-sheet that folds in vitro in microseconds and forms amyloid fibers under physiological conditions. We found from exhaustive ala...
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| Autors principals: | , , , , , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
National Academy of Sciences
2006
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1637568/ https://ncbi.nlm.nih.gov/pubmed/17060612 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0607815103 |
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