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Inhibition of multiple phases of human immunodeficiency virus type 1 replication by a dithiane compound that attacks the conserved zinc fingers of retroviral nucleocapsid proteins.

The human immunodeficiency virus type 1 (HIV-1) nucleocapsid p7 protein contains two retrovirus-type zinc finger domains that are required for multiple phases of viral replication. Chelating residues (three Cys residues and one His residue) of the domains are absolutely conserved among all strains o...

詳細記述

保存先:
書誌詳細
出版年:Antimicrob Agents Chemother
主要な著者: Rice, W G, Baker, D C, Schaeffer, C A, Graham, L, Bu, M, Terpening, S, Clanton, D, Schultz, R, Bader, J P, Buckheit, R W, Field, L, Singh, P K, Turpin, J A
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Microbiology (ASM) 1997
主題:
オンライン・アクセス:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC163723/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9021201/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.41.2.419
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