Inhibition of multiple phases of human immunodeficiency virus type 1 replication by a dithiane compound that attacks the conserved zinc fingers of retroviral nucleocapsid proteins.

The human immunodeficiency virus type 1 (HIV-1) nucleocapsid p7 protein contains two retrovirus-type zinc finger domains that are required for multiple phases of viral replication. Chelating residues (three Cys residues and one His residue) of the domains are absolutely conserved among all strains o...

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Detalhes bibliográficos
Main Authors: Rice, W G, Baker, D C, Schaeffer, C A, Graham, L, Bu, M, Terpening, S, Clanton, D, Schultz, R, Bader, J P, Buckheit, R W, Field, L, Singh, P K, Turpin, J A
Formato: Artigo
Idioma:Inglês
Publicado em: 1997
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC163723/
https://ncbi.nlm.nih.gov/pubmed/9021201
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