Inhibition of multiple phases of human immunodeficiency virus type 1 replication by a dithiane compound that attacks the conserved zinc fingers of retroviral nucleocapsid proteins.

The human immunodeficiency virus type 1 (HIV-1) nucleocapsid p7 protein contains two retrovirus-type zinc finger domains that are required for multiple phases of viral replication. Chelating residues (three Cys residues and one His residue) of the domains are absolutely conserved among all strains o...

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Pubblicato in:	Antimicrob Agents Chemother
Autori principali:	Rice, W G, Baker, D C, Schaeffer, C A, Graham, L, Bu, M, Terpening, S, Clanton, D, Schultz, R, Bader, J P, Buckheit, R W, Field, L, Singh, P K, Turpin, J A
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 1997
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC163723/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9021201/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.41.2.419
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