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Inhibition of multiple phases of human immunodeficiency virus type 1 replication by a dithiane compound that attacks the conserved zinc fingers of retroviral nucleocapsid proteins.

The human immunodeficiency virus type 1 (HIV-1) nucleocapsid p7 protein contains two retrovirus-type zinc finger domains that are required for multiple phases of viral replication. Chelating residues (three Cys residues and one His residue) of the domains are absolutely conserved among all strains o...

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Dades bibliogràfiques
Publicat a:Antimicrob Agents Chemother
Autors principals: Rice, W G, Baker, D C, Schaeffer, C A, Graham, L, Bu, M, Terpening, S, Clanton, D, Schultz, R, Bader, J P, Buckheit, R W, Field, L, Singh, P K, Turpin, J A
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology (ASM) 1997
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC163723/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9021201/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.41.2.419
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