Hypothesis on the mechanism of resistance to fluconazole in Histoplasma capsulatum.

An AIDS patient with disseminated histoplasmosis who improved during treatment with fluconazole but remained fungemic and subsequently relapsed is described. Isolates obtained from blood during therapy showed a progressive increase in fluconazole MIC from 0.625 to 20 micrograms/ml. The pretreatment,...

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Veröffentlicht in:	Antimicrob Agents Chemother
Hauptverfasser:	Wheat, J, Marichal, P, Vanden Bossche, H, Le Monte, A, Connolly, P
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Microbiology (ASM) 1997
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC163721/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9021199/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.41.2.410
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